Actin Chromobody: Visualization of actin dynamics …

Everybody really wants to use a detection probe that does not influence its target. For measurement of actin and actin-related functions there are a number of actin visualization probes and techniques available that researchers can select. Hence, one should only apply such actin visualization probes, which do not alter actin dynamics. … – Read more

New limit in protein complex stability: …

Although traditional IgG antibodies are often used for immunoprecipitation and protein interaction analysis, GFP-binding protein (GBP, ChromoTek gt-250) and other ChromoTek VHHs ( easily outcompete those under challenging conditions such as elevated temperatures, varying … – Read more

Visualize the onset of metastasis with …

The progression of epithelial cancers into metastatic stages is triggered by a cellular process called “epithelial-mesenchymal transition” (EMT). In response to cytokines, tumor cells shut down the expression of epithelial makers including occludin or E-cadherin and gain mesenchymal markers such as N-cadherin or vimentin. Such cells are … – Read more

  • Max-Planck-Institut für Biophysikalische Chemie Karl-Friedrich-Bonhoeffer-Institut Göttingen
  • The University of Edinburgh
  • Institute of molecular plant sciences
  • Université du Luxembourg
  • The University of Utah
  • uOttawa
  • Universität Zürich