p53-C-term-Trap

Description
The ChromoTek p53-C-term-Trap is an affinity resin for immunoprecipitation of p53.
It consists of an anti-p53 Nanobody/ VHH coupled to beads that binds to the C-terminus of p53.

Specificity
p53
Species-Reactivity: Tested on human, mouse
Isoform: Alpha
Epitope: 302-393 aa

Applications
Immunoprecipitation (IP) / Co-IP
Mass spectrometry (MS)

Formats/matrices
p53-C-term-Trap Agarose
p53-C-term VHH, recombinant binding protein

Synonyms
p53-C-term VHH, p53-C-term Binding-Protein, p53-C-term Nanobody, p53-C-term, or single domain antibody fragment (sdAb)

Benefit from p53-C-term-Trap for Immunoprecipitation (IP)

  • Immunoprecipitation of human and mice p53 isoforms alpha with p53-C-term-Trap
  • Pull-down of the human p53 proteome with complementary p53-N-term- and p53-C-term-Traps, e.g. p53 isoforms and variants
  • No heavy & light antibody chains in your downstream application
  • Short incubation time (60 min at +4°C)
  • Strong binding even under harsh washing conditions

Format/matrices & properties

We offer the p53-C-term VHH coupled to agarose beads or uncoupled as purified protein.

Extraordinary stable & reliable binding

  • Fully applications validated and characterized

About p53

The tumor suppressor protein p53 plays a major role in cell cycle control, apoptosis and senescence.

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Only for research applications, not for diagnostic or therapeutic use!