Our new tool for detection of actin in live cells, the Actin-Chromobody®, lets you monitor the assembly/ disassembly of cytoskeleton in real time. Take advantage of the small size of the Chromobody® and produce stunning high resolution pictures and movies of the cytoskeleton's dynamics.
- Easily transfect your cells and non-invasively visualize actin cytoskeleton in real time
- Target and trace microfilaments in your cell line of interest
- Use Actin-Chromobody® as a marker of cellular morphology and as a probe for cellular motility
- Actin-Chromobody® does not affect cell viability or migration.
Live visualization of actin dynamics with Actin-Chromobody®
Actin Chromobody® allows monitoring of actin dynamics in real time in living cells. HeLa cells were subjected to confocal imaging upon treatment with 2 µM of Cytochalasin D for 1 hour and recovery for 2 hours. Time lapse analysis revealing actin reorganization is shown.
Actin-Chromobody® in various cell lines
Advantages of using Actin-Chromobody® to test actin dynamics
|Live cell imaging||- (toxic)||+||++|
|Influence on actin dynamics||-- (toxic)||- (high)||++ (none)|