GST-Trap

Our GST-Trap is a high quality Glutathione S-Transferase (GST)-binding protein coupled to magnetic particles for biochemical analysis of GST fusion proteins and their interacting partners.

Fusion of proteins to Schistosoma japonicum GST is a common technique to increase solubility and expression level of a protein. Furthermore, GST- tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. 

Use GST-Trap for:

  • Immunoprecipitation (IP) / Co-IP
  • Mass spectrometry
  • Enzyme activity measurements
  • ChIP/ RIP analysis

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Very high binding affinity:
The GST-Trap effectively immunoprecipitates GST-fusion proteins at very low concentrations. See Western Blot (below): Compared to glutathione cellulose, the GST-Trap has a considerably higher affinity.

High affinity GST matrix