Poly (ADP-ribose) polymerase 1 (PARP1) is one of the most abundant proteins in the nucleus and is involved in many cellular processes like DNA repair, transcriptional regulation, and modulation of chromatin structure. Our PARP1-Trap is a high quality PARP1-binding protein coupled to a monovalent matrix (agarose particles) for biochemical analysis of PARP1 and interacting partners.
- Immunoprecipitation (IP)/ Co-IP
- Mass spectrometry
- Enzyme activity measurements